Wednesday, March 4, 2009

Folate Deficiency Triples Risk Of Alzheimer's

Nutritional scientists used to think the key to a long and healthy life lay in antioxidants, and health conscious people, including me, were taking lots of vitamins C and E. Couldn’t hurt and might help, we thought. Then research showed that people taking more than 400 IU of vitamin E per day had a 10% higher risk of death compared to those who did not! My vitamin E capsules went down the drain that very day, and I felt that the scientists of the world had led me down the primrose path.

Now the future seems to lie, not in plastics, but in folates. And the research seems solid. So solid that my 78-year-old husband’s doctor has him taking supplements of folic acid, the pharmaceutical equivalent of the folates in food.

Remember the Kame Project, in which subjects who drank fruit or vegetable juice more than three times a week cut their risk of Alzheimer’s by a whopping 76%? Well, every year it seems more likely that it’s the folates in those fruits and vegetables that were working those wonders.

In fact, the latest research, as reported on February 5, 2008, in Science Daily, found that folate deficiency is associated with a tripling in the risk of developing dementia among elderly people.

Where Do We Find These Folates?


Folates occur most often in leafy vegetables such as spinach, turnip greens, lettuces, dried beans and peas, and in certain fruits. Here is a chart from the NIH Office Of Dietary Supplements. As you can see, both tomato juice and orange juice are fairly good sources, and I assume those were the main things the Kame Project subjects, the ones who cut their risk of Alzheimer’s by 76%, were drinking on a regular basis.

The one-a-day vitamin capsules that my husband and I take also supply 100% of our daily requirement of folic acid, giving us one more reason we should take those daily vitamins. The vitamin manufacturers obviously keep up with the scientific literature, and I appreciate this more every year.

Here are some earlier posts about the relation between diet and Alzheimer’s:

Live Longer With The Mediterranean Diet

It’s Scary – I’m Forgetting Things

Prevent Alzheimer’s With Good Cholesterol

Prevent Alzheimer’s By Your Diet